BHLHE22

Across TCGA patient cohorts, BHLHE22 protein abundance is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BHLHE22-associated genes across cancer lineages are C1QL1, C9orf78, and EVI5L. Each is linked with BHLHE22 in more than 1 cancer types. Because this analysis shows association rather than direction, both BHLHE22-to-partner and partner-to-BHLHE22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BHLHE22 versus C1QL1 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHE22→partner) and Y-score (partner→BHLHE22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C1QL1 →	+1.777	+2.264	.006	.009	3	1
BRCA	C9orf78 →	+0.599	+2.896	<.001	.007	3	1
BRCA	EVI5L →	+1.270	+2.454	.003	.009	3	1
BRCA	PFKM →	+1.658	+2.416	.006	.009	3	1
BRCA	NOXRED1 →	+1.032	+2.972	<.001	.007	3	1
BRCA	TARS3 →	+0.525	+2.695	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

BHLHE22 vs C1QL1 — BRCA

Explore this scatter interactively →