Across TCGA patient cohorts, BHLHB9 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BHLHB9-associated genes across cancer lineages are ERK2, FoxM1, and PDCD4. Each is linked with BHLHB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both BHLHB9-to-partner and partner-to-BHLHB9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHB9→partner) and Y-score (partner→BHLHB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.142	+1.514	.012	.014	3	2
UCEC	FoxM1 →	+0.181	+1.637	.017	.001	3	2
UCEC	PDCD4 →	-0.494	-2.087	<.001	.004	3	2
UCEC	Rab25 →	-0.253	-1.999	.009	.008	3	2
UCEC	Shc_pY317 →	-0.148	-1.999	<.001	.002	3	2
UCEC	STAT3_pY705 →	-0.344	-2.000	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration

BHLHB9 survival (RNA) · tumor vs normal (RNA) · all BHLHB9 data types