Across TCGA cell cohorts, BHLHB9 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BHLHB9-associated genes across cancer lineages are OCM2, FABP9, and KIR3DL1. Each is linked with BHLHB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both BHLHB9-to-partner and partner-to-BHLHB9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BHLHB9→partner) and Y-score (partner→BHLHB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.036	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	FABP9 →	+0.031	+4.662	<.001	.005	3	1
BLOOD_Leukemia	KIR3DL1 →	+0.033	+4.276	<.001	.007	3	1
BLOOD_Leukemia	KRTAP21-2 →	+0.062	+4.539	.001	.007	3	1
BLOOD_Leukemia	FAM24A →	+0.061	+4.969	<.001	.003	3	1
BLOOD_Leukemia	IQCF5 →	+0.103	+5.786	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

BHLHB9 survival (RNA) · tumor vs normal (RNA) · all BHLHB9 data types