BHLHA15

Across TCGA pan-cancer cohorts, BHLHA15 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated BHLHA15 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher BHLHA15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BHLHA15 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where BHLHA15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.725	0.321	.004	17	view →
PDAC	OS	Quartile	III,IV	0.760	0.423	.020	3	view →
LSCC	OS	Quartile	All	1.000	0.821	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

BHLHA15–LUAD (DFS)

Open the LUAD breakdown →