BGN

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BGN RNA expression is significantly associated with the protein abundance of many other proteins, with 18,695 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BGN-associated proteins across cancer lineages are RCN3, CCDC80, and AEBP1. Each is linked with BGN in more than 9 cancer types. Because this analysis shows association rather than direction, both BGN-to-partner and partner-to-BGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BGN versus RCN3 in GBM, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BGN→partner) and Y-score (partner→BGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRCN3 →+0.689+0.765<.001<.001310
BRCACCDC80 →+0.942+1.522<.001<.001310
OVAEBP1 →+0.932+2.622<.001<.001310
OVCNN2 →+0.809+2.431<.001<.001310
COADCOL1A1 →+0.963+2.384<.001<.001310
COADCOL3A1 →+0.867+2.300<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,695 associations by consensus.

BGN vs RCN3 — GBM

Per-sample scatter of BGN vs RCN3 in GBM (Pearson r = 0.69).

Explore this scatter interactively →

Exploration