BGN

Across TCGA patient cohorts, BGN protein abundance is significantly associated with the RNA expression of many other genes, with 16,017 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BGN-associated genes across cancer lineages are MGP, PDGFRB, and CCN2. Each is linked with BGN in more than 9 cancer types. Because this analysis shows association rather than direction, both BGN-to-partner and partner-to-BGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BGN versus MGP in COAD, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BGN→partner) and Y-score (partner→BGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MGP →	+1.788	+0.798	<.001	<.001	3	10
OV	PDGFRB →	+1.470	+0.730	<.001	<.001	3	10
OV	CCN2 →	+1.799	+0.921	<.001	<.001	3	10
OV	AOC3 →	+1.491	+0.798	<.001	<.001	3	10
OV	LRRC32 →	+1.161	+0.724	<.001	<.001	3	10
CCRCC	HEYL →	+1.184	+0.851	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,017 associations by consensus.

BGN vs MGP — COAD

Explore this scatter interactively →