BGN

Across TCGA cell cohorts, BGN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,509 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BGN-associated GO terms across cancer lineages are Collagen biosynthetic process, RNA export from nucleus, and Nucleic acid transport. Each is linked with BGN in more than 8 cancer types. Because this analysis shows association rather than direction, both BGN-to-partner and partner-to-BGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen biosynthetic process grouped by BGN-low versus BGN-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BGN→partner) and Y-score (partner→BGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Collagen biosynthetic process →	+0.197	+3.024	<.001	<.001	3	9
BREAST	RNA export from nucleus →	+0.073	+1.669	<.001	.007	3	9
BREAST	Nucleic acid transport →	+0.064	+2.092	.003	.005	3	8
BREAST	RNA transport →	+0.064	+2.092	.003	.005	3	8
BREAST	Establishment of RNA localization →	+0.061	+2.155	.003	.003	3	8
BLOOD_Lymphoma	Protein polyubiquitination →	+0.028	+0.170	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,509 associations by consensus.

Collagen biosynthetic process by BGN expression — CNS

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