BGLAP

Across TCGA patient cohorts, BGLAP mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible BGLAP-associated genes across cancer lineages are MIR4673, MIR548AC, and RN7SL140P. Each is linked with BGLAP in more than 1 cancer types. Because this analysis shows association rather than direction, both BGLAP-to-partner and partner-to-BGLAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4673 grouped by BGLAP-low versus BGLAP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BGLAP→partner) and Y-score (partner→BGLAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4673 →	+0.818	+4.982	<.001	.009	3	1
UCEC	MIR548AC →	+0.830	+5.242	<.001	.007	3	1
UCEC	RN7SL140P →	+0.341	+6.582	<.001	.001	3	1
UCEC	MIR6857 →	+0.777	+5.358	<.001	.006	3	1
BLCA	LINC01148 →	+0.053	+5.106	<.001	.008	3	1
BLCA	SNRPGP20 →	+0.260	+5.411	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

MIR4673 by BGLAP expression — UCEC

Explore this box plot interactively →