BFSP2

Across TCGA cell cohorts, BFSP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,721 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BFSP2-associated GO terms across cancer lineages are Positive regulation of transcription initiation by RNA polymerase II, Positive regulation of interleukin-1 production, and Negative regulation of T-helper 2 cell differentiation. Each is linked with BFSP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both BFSP2-to-partner and partner-to-BFSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription initiation by RNA polymerase II grouped by BFSP2-low versus BFSP2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BFSP2→partner) and Y-score (partner→BFSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of transcription initiation by RNA polymerase II →	+0.047	+0.656	<.001	.004	3	6
BREAST	Positive regulation of interleukin-1 production →	-0.081	-0.582	.001	.006	3	5
BLOOD_Myeloma	Negative regulation of T-helper 2 cell differentiation →	-0.943	-1.803	.001	.006	3	5
BREAST	Positive regulation of coagulation →	-0.184	-0.783	<.001	.004	3	5
BREAST	Purine nucleoside triphosphate biosynthetic process →	+0.081	+0.742	<.001	.006	2	6
BREAST	Purine ribonucleoside triphosphate biosynthetic process →	+0.081	+0.742	<.001	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,721 associations by consensus.

Positive regulation of transcription initiation by RNA polymerase II by BFSP2 expression — BLOOD_Leukemia

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