BFSP1

Across TCGA cell cohorts, BFSP1 mutation is significantly associated with the RNA expression of many other genes, with 55 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BFSP1-associated genes across cancer lineages are ZSCAN1, PRKACG, and TBL1Y. Each is linked with BFSP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BFSP1-to-partner and partner-to-BFSP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSCAN1 grouped by BFSP1-low versus BFSP1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BFSP1→partner) and Y-score (partner→BFSP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ZSCAN1 →	+0.039	+5.000	<.001	.006	3	1
PANCREAS	PRKACG →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	TBL1Y →	+0.006	+5.614	<.001	.002	3	1
OESOPHAGUS	SLC5A8 →	+0.070	+4.906	<.001	.006	3	1
LARGE_INTESTINE	CCDC47 →	+0.652	+3.212	<.001	.006	3	1
LARGE_INTESTINE	DCLRE1B →	+0.559	+3.212	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

ZSCAN1 by BFSP1 expression — PANCREAS

Explore this box plot interactively →