BFAR

Across TCGA patient cohorts, BFAR protein abundance is significantly associated with the RNA expression of many other genes, with 1,055 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BFAR-associated genes across cancer lineages are ACOX3, TTYH2, and TAGLN2. Each is linked with BFAR in more than 1 cancer types. Because this analysis shows association rather than direction, both BFAR-to-partner and partner-to-BFAR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BFAR versus ACOX3 in CCRCC, with a Pearson correlation of 0.94.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BFAR→partner) and Y-score (partner→BFAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ACOX3 →	+0.413	+0.966	.002	.003	3	2
HNSC	TTYH2 →	+0.821	+0.483	.006	.004	3	2
LUAD	TAGLN2 →	+1.007	+0.677	.001	.002	3	2
HNSC	ROR2 →	+2.457	+0.700	<.001	.001	3	2
LSCC	ATOX1 →	+0.426	+0.419	.003	.001	3	2
LSCC	TSPAN17 →	+0.830	+0.539	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,055 associations by consensus.

BFAR vs ACOX3 — CCRCC

Explore this scatter interactively →