BFAR

Across TCGA cell cohorts, BFAR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,995 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BFAR-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cell PML body, Telomerase RNA stabilization, and Phosphatidylinositol metabolic process. Each is linked with BFAR in more than 11 cancer types. Because this analysis shows association rather than direction, both BFAR-to-partner and partner-to-BFAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cell PML body grouped by BFAR-low versus BFAR-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BFAR→partner) and Y-score (partner→BFAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cell PML body →	+0.108	+0.719	<.001	<.001	3	12
BREAST	Telomerase RNA stabilization →	+0.102	+0.549	.002	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.044	+0.670	.003	.002	3	9
STOMACH	Negative regulation of IRE1-mediated unfolded protein response →	+0.086	+0.650	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Response to toxic substance →	-0.082	-0.598	<.001	<.001	3	8
BONE	Phosphatidylinositol biosynthetic process →	+0.043	+0.406	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

Symbiont-mediated disruption of host cell PML body by BFAR expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →