BEX4

Across TCGA patient cohorts, BEX4 protein abundance is significantly associated with the RNA expression of many other genes, with 3,711 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BEX4-associated genes across cancer lineages are SNAP25, RN7SL688P, and GRIN1. Each is linked with BEX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEX4-to-partner and partner-to-BEX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEX4 versus SNAP25 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX4→partner) and Y-score (partner→BEX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNAP25 →	+1.723	+0.482	<.001	.008	3	2
LSCC	RN7SL688P →	+0.703	+1.253	.006	.003	3	2
GBM	GRIN1 →	+1.304	+0.516	.001	.003	3	2
LSCC	SLC1A5 →	+0.822	+0.937	.001	.002	3	1
LSCC	MAG →	-0.178	-0.937	.006	.002	3	1
LSCC	CACNG1 →	+0.413	+0.938	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,711 associations by consensus.

BEX4 vs SNAP25 — GBM

Explore this scatter interactively →