BEX4

Across TCGA patient cohorts, BEX4 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,526 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BEX4-associated proteins across cancer lineages are RETREG3_S26, RGCC_T111, and RGS12_T1287. Each is linked with BEX4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEX4-to-partner and partner-to-BEX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEX4 versus RETREG3_S26 in GBM, with a Pearson correlation of -0.33.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX4→partner) and Y-score (partner→BEX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RETREG3_S26 →	-0.368	-0.560	.003	<.001	3	1
GBM	RGCC_T111 →	+0.590	+0.597	.001	<.001	3	1
GBM	RGS12_T1287 →	-0.431	-0.746	.002	.002	3	1
GBM	RHEB_S130 →	-0.797	-0.536	.001	<.001	3	1
GBM	RIMS2_S236 →	+1.288	+0.609	<.001	<.001	3	1
GBM	RIMS2_S482 →	+0.876	+0.609	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,526 associations by consensus.

BEX4 vs RETREG3_S26 — GBM

Explore this scatter interactively →