BEX4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, BEX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,152 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BEX4-associated GO terms across cancer lineages are Negative regulation of tubulin deacetylation, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with BEX4 in more than 18 cancer types. Because this analysis shows association rather than direction, both BEX4-to-partner and partner-to-BEX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of tubulin deacetylation grouped by BEX4-low versus BEX4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX4→partner) and Y-score (partner→BEX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONENegative regulation of tubulin deacetylation →+1.794+3.956<.001<.001319
OESOPHAGUSRegulation of myoblast fusion →+0.150+2.943<.001.003315
OESOPHAGUSRegulation of syncytium formation by plasma membrane fusion →+0.143+2.920<.001.004314
OESOPHAGUSNegative regulation of syncytium formation by plasma membrane fusion →+0.123+2.033<.001<.001314
LUNG_SCLCRegulation of proteasomal ubiquitin-dependent protein catabolic process →+0.041+1.863<.001<.001313
OESOPHAGUSRegulation of proteasomal protein catabolic process →+0.093+2.697<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

Negative regulation of tubulin deacetylation by BEX4 expression — BONE

Box plot of Negative regulation of tubulin deacetylation in BEX4-low vs BEX4-high samples in BONE.

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Exploration