BEX2

Across TCGA patient cohorts, BEX2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,412 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BEX2-associated genes across cancer lineages are KLHL10, FBXO40, and VTRNA1-3. Each is linked with BEX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BEX2-to-partner and partner-to-BEX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEX2 versus KLHL10 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEX2→partner) and Y-score (partner→BEX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLHL10 →	+0.261	+0.346	.002	.002	3	4
HNSC	FBXO40 →	+0.752	+0.390	.001	<.001	3	4
CCRCC	VTRNA1-3 →	+2.832	+0.535	<.001	<.001	3	4
LSCC	C1orf146 →	+0.357	+0.625	<.001	<.001	3	4
LSCC	RPL23AP72 →	+0.582	+0.711	<.001	<.001	3	4
HNSC	SMIM33 →	+0.316	+0.479	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,412 associations by consensus.

BEX2 vs KLHL10 — HNSC

Explore this scatter interactively →