BET1P1

Across TCGA pan-cancer cohorts, BET1P1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BET1P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where BET1P1 RNA is repressed in tumor relative to normal tissue. In most cancer types BET1P1 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and LUSC are the cancer types where BET1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BET1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	−0.506	<.001	11	view →
KICH	Male	All	−0.588	<.001	8	view →
LUSC	Female	All	−0.979	<.001	7	view →
LUAD	Female	All	−0.806	<.001	7	view →
BRCA	All	III,IV	−0.609	<.001	6	view →
UCEC	All	All	−0.427	<.001	6	view →
COAD	Female	II,III,IV	−0.228	<.001	5	view →
BLCA	All	All	−0.262	.012	2	view →
HNSC	Female	IV	+0.191	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

BET1P1–KIRP

Open the KIRP breakdown →