BET1L

Across TCGA pan-cancer cohorts, BET1L RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated BET1L data layer compared with 2 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher BET1L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BET1L expression acts as an unfavorable survival marker, although some lineages such as KIRC and CHOL show a favorable association.

KICH, LIHC, and ACC are the cancer types where BET1L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.257	0.931	.002	63	view →
LIHC	DFS	Median	All	0.467	0.616	<.001	61	view →
ACC	DFS	Median	All	0.248	0.639	<.001	54	view →
KIRC	DFS	Tertile	All	0.714	0.547	.001	49	view →
CHOL	OS	Tertile	All	0.906	0.359	.002	45	view →
LGG	OS	Median	All	0.852	0.937	<.001	36	view →
KIRP	DFS	Median	II,III,IV	0.542	0.806	.006	36	view →
HNSC	OS	Tertile	III,IV	0.565	0.822	.004	20	view →
LUSC	DFS	Quartile	III,IV	0.211	0.482	.008	19	view →
PAAD	DFS	Median	All	0.388	0.636	.003	19	view →
SKCM	OS	Median	All	0.826	0.739	.002	17	view →
UVM	DFS	Tertile	II,III,IV	0.337	0.874	.009	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

BET1L–KICH (DFS)

Open the KICH breakdown →