Across TCGA pan-cancer cohorts, BET1L Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BET1L data layer compared with 23 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher BET1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BET1L expression acts as an unfavorable survival marker.
HNSC and PRAD are the cancer types where BET1L Mutation most reproducibly stratifies survival.