BEST3

Across TCGA patient cohorts, BEST3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,335 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BEST3-associated proteins across cancer lineages are RAB3IP, PRKAA2, and ADSS2. Each is linked with BEST3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BEST3-to-partner and partner-to-BEST3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEST3 versus RAB3IP in GBM, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BEST3→partner) and Y-score (partner→BEST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAB3IP →	+0.617	+1.150	<.001	<.001	3	3
HNSC	PRKAA2 →	+0.640	+1.589	<.001	<.001	3	3
PDAC	ADSS2 →	-0.269	-0.202	<.001	.002	3	3
UCEC	HSPA12A →	+0.733	+1.437	<.001	<.001	3	3
UCEC	STXBP1 →	+0.596	+1.332	.001	<.001	3	3
BRCA	PHPT1 →	+0.302	+0.174	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,335 associations by consensus.

BEST3 vs RAB3IP — GBM

Explore this scatter interactively →