BEST3

Across TCGA cell cohorts, BEST3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,050 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible BEST3-associated GO terms across cancer lineages are Monocarboxylic acid transport, Meiotic sister chromatid cohesion, centromeric, and Positive regulation of cell-substrate junction organization. Each is linked with BEST3 in more than 8 cancer types. Because this analysis shows association rather than direction, both BEST3-to-partner and partner-to-BEST3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocarboxylic acid transport grouped by BEST3-low versus BEST3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEST3→partner) and Y-score (partner→BEST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Monocarboxylic acid transport →	-0.073	-0.541	.001	.007	3	9
BLOOD_Leukemia	Meiotic sister chromatid cohesion, centromeric →	+0.105	+1.963	<.001	<.001	3	8
LIVER	Positive regulation of cell-substrate junction organization →	+0.104	+1.182	.003	<.001	3	8
URINARY_TRACT	Pressure natriuresis →	-0.797	-0.551	.009	.003	3	8
BLOOD_Leukemia	Regulation of metaphase/anaphase transition of cell cycle →	+0.060	+1.940	.002	<.001	2	8
BLOOD_Leukemia	Regulation of chromosome separation →	+0.072	+1.588	.003	.003	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,050 associations by consensus.

Monocarboxylic acid transport by BEST3 expression — BONE

Explore this box plot interactively →