BEND7

Across TCGA pan-cancer cohorts, BEND7 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BEND7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BEND7 RNA is repressed in tumor relative to normal tissue. In most cancer types BEND7 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and LUSC are the cancer types where BEND7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BEND7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−1.047	<.001	10	view →
BRCA	All	III,IV	−1.504	<.001	6	view →
LUSC	All	III,IV	−1.421	<.001	6	view →
UCEC	All	All	−1.113	<.001	6	view →
LUAD	Female	II,III,IV	−0.980	<.001	6	view →
LIHC	All	All	+0.469	<.001	6	view →
HNSC	Female	IV	−1.014	.032	2	view →
THCA	All	All	−0.259	.018	2	view →
CHOL	All	All	+0.716	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

BEND7–KICH

Open the KICH breakdown →