BEND6

Across TCGA cell cohorts, BEND6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,764 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BEND6-associated GO terms across cancer lineages are Collagen biosynthetic process, Regulation of ATP-dependent activity, and Positive regulation of protein ubiquitination. Each is linked with BEND6 in more than 11 cancer types. Because this analysis shows association rather than direction, both BEND6-to-partner and partner-to-BEND6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen biosynthetic process grouped by BEND6-low versus BEND6-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEND6→partner) and Y-score (partner→BEND6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Collagen biosynthetic process →	+0.255	+1.718	.001	.002	3	12
BLOOD_Myeloma	Regulation of ATP-dependent activity →	+0.100	+1.141	<.001	<.001	3	12
BONE	Positive regulation of protein ubiquitination →	+0.078	+1.870	.002	<.001	3	12
SOFT_TISSUE	Positive regulation of supramolecular fiber organization →	+0.079	+1.701	<.001	<.001	3	11
SOFT_TISSUE	Maintenance of protein location in cell →	+0.132	+1.571	<.001	<.001	3	11
SOFT_TISSUE	Regulation of collagen metabolic process →	+0.145	+1.218	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,764 associations by consensus.

Collagen biosynthetic process by BEND6 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →