BEND5

Across TCGA cell cohorts, BEND5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,700 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BEND5-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of DNA repair, and Positive regulation of T cell differentiation. Each is linked with BEND5 in more than 8 cancer types. Because this analysis shows association rather than direction, both BEND5-to-partner and partner-to-BEND5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by BEND5-low versus BEND5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEND5→partner) and Y-score (partner→BEND5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of chromosome condensation →	+0.115	+1.817	.003	.003	3	9
BONE	Positive regulation of DNA repair →	+0.080	+2.336	<.001	<.001	3	9
LUNG_SCLC	Positive regulation of T cell differentiation →	+0.065	+1.324	<.001	<.001	3	8
URINARY_TRACT	Positive regulation of lymphocyte differentiation →	+0.088	+1.064	.002	.004	3	8
OVARY	Negative regulation of myoblast fusion →	+0.106	+0.834	<.001	.003	3	8
LUNG_SCLC	U2-type prespliceosome assembly →	+0.072	+1.691	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,700 associations by consensus.

Negative regulation of chromosome condensation by BEND5 expression — BONE

Explore this box plot interactively →