Across TCGA patient cohorts, BEND4 mutation is significantly associated with the RNA expression of many other genes, with 2,904 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BEND4-associated genes across cancer lineages are MIR6509, RCCD1, and PBK. Each is linked with BEND4 in more than 2 cancer types. Because this analysis shows association rather than direction, both BEND4-to-partner and partner-to-BEND4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEND4→partner) and Y-score (partner→BEND4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MIR6509 →	+0.960	+5.039	<.001	.008	3	3
UCEC	RCCD1 →	+0.444	+1.869	<.001	.005	3	3
UCEC	PBK →	+1.092	+3.403	<.001	<.001	3	3
UCEC	DEPDC1B →	+0.683	+2.609	.004	.006	3	3
UCEC	TIPIN →	+0.549	+2.758	<.001	<.001	3	3
UCEC	ORC6 →	+0.831	+2.747	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,904 associations by consensus.

Exploration

BEND4 survival (RNA) · tumor vs normal (RNA) · all BEND4 data types