Across TCGA cell cohorts, BEND4 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible BEND4-associated genes across cancer lineages are TEX26, MEIKIN, and ODF1. Each is linked with BEND4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEND4-to-partner and partner-to-BEND4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEND4→partner) and Y-score (partner→BEND4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TEX26 →	+0.035	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	MEIKIN →	+0.085	+4.887	.002	.009	3	1
SKIN	ODF1 →	+0.016	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CLEC18C →	+0.153	+3.555	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

BEND4 survival (RNA) · tumor vs normal (RNA) · all BEND4 data types