BEN domain containing 3 pseudogene 3Genealiases: []
Q-omics provides the consensus-scored BEND3P3 profile across patient tissues and cancer cell-line models. BEND3P3 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, BEND3P3 is differentially expressed in 12, with the highest sampling consensus in BLCA. Additionally, BEND3P3 RNA expression shows 20,129 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight SKCM, BLCA, and THYM as cancer lineages where BEND3P3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for BEND3P3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes BEND3P3 survival associations across molecular data types. BEND3P3 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible BEND3P3 RNA expression–survival associations across cancer types. High BEND3P3 expression shows unfavorable associations in CESC, MESO and THCA, but favorable associations in SKCM, KIRC and HNSC. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify SKCM as the clearest survival context for BEND3P3 RNA expression.
This table summarizes BEND3P3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for BEND3P3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. BEND3P3 shows lower tumor expression in BLCA, KICH, THCA, BRCA, LUAD and LUSC. The BLCA box plot shows higher BEND3P3 RNA expression in normal versus tumor tissue (log2 FC = −1.120, t-test p = .002).
This table shows molecular features associated with BEND3P3 in patient tissues and cancer cell lines. In patient samples, BEND3P3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
