BEND3

Across TCGA cell cohorts, BEND3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,873 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BEND3-associated GO terms across cancer lineages are Nucleosome disassembly, DNA-templated DNA replication, and Regulation of DNA repair. Each is linked with BEND3 in more than 17 cancer types. Because this analysis shows association rather than direction, both BEND3-to-partner and partner-to-BEND3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by BEND3-low versus BEND3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BEND3→partner) and Y-score (partner→BEND3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleosome disassembly →	+0.250	+1.079	<.001	<.001	3	18
BONE	DNA-templated DNA replication →	+0.104	+0.844	<.001	<.001	3	17
BONE	Regulation of DNA repair →	+0.103	+1.025	<.001	<.001	3	17
BONE	Protein-DNA complex organization →	+0.102	+0.855	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	DNA replication checkpoint signaling →	+0.189	+0.668	<.001	<.001	3	17
PANCREAS	Regulation of DNA-templated DNA replication →	+0.102	+0.751	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,873 associations by consensus.

Nucleosome disassembly by BEND3 expression — BONE

Explore this box plot interactively →