Across TCGA patient cohorts, BEGAIN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,979 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BEGAIN-associated proteins across cancer lineages are SARM1, TMOD2, and PDLIM7. Each is linked with BEGAIN in more than 5 cancer types. Because this analysis shows association rather than direction, both BEGAIN-to-partner and partner-to-BEGAIN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BEGAIN→partner) and Y-score (partner→BEGAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SARM1 →	+0.492	+0.394	<.001	<.001	3	6
UCEC	TMOD2 →	+0.597	+0.424	<.001	<.001	3	4
UCEC	PDLIM7 →	+0.879	+0.353	<.001	<.001	3	4
UCEC	ANXA1 →	-0.690	-0.376	.001	<.001	3	4
LSCC	CRMP1 →	+0.643	+0.309	.002	.004	3	4
UCEC	FERMT2 →	+0.764	+0.351	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,979 associations by consensus.

Exploration

BEGAIN survival (RNA) · tumor vs normal (RNA) · all BEGAIN data types