Across TCGA patient cohorts, BEGAIN protein abundance is significantly associated with the RNA expression of many other genes, with 2,911 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BEGAIN-associated genes across cancer lineages are SLC25A41, RN7SL79P, and ACRBP. Each is linked with BEGAIN in more than 1 cancer types. Because this analysis shows association rather than direction, both BEGAIN-to-partner and partner-to-BEGAIN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEGAIN→partner) and Y-score (partner→BEGAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC25A41 →	+0.371	+0.502	.001	.001	3	2
GBM	RN7SL79P →	+0.398	+0.404	<.001	<.001	3	2
PDAC	ACRBP →	+0.649	+0.538	<.001	.005	3	1
PDAC	LGALS8 →	-0.337	-0.398	.003	.003	3	1
PDAC	IL17B →	+0.288	+0.431	.004	<.001	3	1
PDAC	PSPH →	-0.691	-0.501	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

Exploration

BEGAIN survival (RNA) · tumor vs normal (RNA) · all BEGAIN data types