Across TCGA patient cohorts, BEGAIN mutation is significantly associated with the RNA expression of many other genes, with 937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BEGAIN-associated genes across cancer lineages are RPL26L1, NF1P10, and CYCSP29. Each is linked with BEGAIN in more than 2 cancer types. Because this analysis shows association rather than direction, both BEGAIN-to-partner and partner-to-BEGAIN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEGAIN→partner) and Y-score (partner→BEGAIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL26L1 →	+0.478	+2.447	.001	.001	3	3
UCEC	NF1P10 →	+0.113	+2.078	.007	.006	3	2
BLCA	CYCSP29 →	+0.244	+4.533	<.001	.005	3	2
UCEC	EIF3M →	+0.491	+2.447	.003	.001	3	2
UCEC	TATDN2 →	+0.319	+2.609	.005	.006	3	2
UCEC	COX18 →	+0.487	+3.513	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 937 associations by consensus.

Exploration

BEGAIN survival (RNA) · tumor vs normal (RNA) · all BEGAIN data types