Across TCGA patient cohorts, BECN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,016 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BECN2-associated GO terms across cancer lineages are Protein polyubiquitination, Regulation of binding, and Regulation of type I interferon-mediated signaling pathway. Each is linked with BECN2 in more than 21 cancer types. Because this analysis shows association rather than direction, both BECN2-to-partner and partner-to-BECN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BECN2→partner) and Y-score (partner→BECN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein polyubiquitination →	+0.061	+0.221	<.001	<.001	3	22
STAD	Regulation of binding →	+0.057	+0.235	<.001	<.001	3	20
ESCA	Regulation of type I interferon-mediated signaling pathway →	+0.076	+0.307	<.001	<.001	3	20
STAD	tRNA metabolic process →	+0.062	+0.244	<.001	<.001	3	20
STAD	Signal transduction in response to DNA damage →	+0.062	+0.237	<.001	<.001	3	20
STAD	Pyrimidine-containing compound metabolic process →	+0.046	+0.262	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,016 associations by consensus.

Exploration

BECN2 survival (RNA) · tumor vs normal (RNA) · all BECN2 data types