BECN1

Across TCGA patient cohorts, BECN1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,358 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BECN1-associated genes across cancer lineages are VSIR, ARHGDIB, and ARRB1. Each is linked with BECN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BECN1-to-partner and partner-to-BECN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BECN1 versus VSIR in OV, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BECN1→partner) and Y-score (partner→BECN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VSIR →	+0.707	+0.207	.001	<.001	3	4
OV	ARHGDIB →	+0.953	+0.219	.002	.003	3	4
LSCC	ARRB1 →	+0.712	+0.165	<.001	<.001	3	4
UCEC	FGD2 →	+0.676	+0.145	<.001	.002	3	4
OV	TNFAIP8L2 →	+0.743	+0.229	.006	.002	3	4
OV	SIGLEC7 →	+0.652	+0.174	.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,358 associations by consensus.

BECN1 vs VSIR — OV

Explore this scatter interactively →