BECN1

Across TCGA cell cohorts, BECN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,778 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BECN1-associated GO terms across cancer lineages are Positive regulation of stress granule assembly, Organelle membrane fusion, and Organelle fusion. Each is linked with BECN1 in more than 14 cancer types. Because this analysis shows association rather than direction, both BECN1-to-partner and partner-to-BECN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress granule assembly grouped by BECN1-low versus BECN1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BECN1→partner) and Y-score (partner→BECN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of stress granule assembly →	+0.126	+0.846	.001	<.001	3	15
BREAST	Organelle membrane fusion →	+0.081	+0.715	<.001	<.001	3	15
BREAST	Organelle fusion →	+0.067	+0.642	<.001	.002	3	14
BREAST	Cytosolic transport →	+0.068	+0.562	<.001	.009	2	14
SOFT_TISSUE	Endosomal transport →	+0.067	+0.810	<.001	<.001	3	12
STOMACH	Vesicle fusion →	+0.066	+0.615	<.001	.004	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,778 associations by consensus.

Positive regulation of stress granule assembly by BECN1 expression — BREAST

Explore this box plot interactively →