BDP1

Across TCGA patient cohorts, BDP1 mutation is significantly associated with the RNA expression of many other genes, with 4,689 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BDP1-associated genes across cancer lineages are BIRC5, ZWINT, and DNAJC9. Each is linked with BDP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BDP1-to-partner and partner-to-BDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BIRC5 grouped by BDP1-low versus BDP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BDP1→partner) and Y-score (partner→BDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BIRC5 →	+0.604	+1.394	<.001	<.001	3	5
UCEC	ZWINT →	+0.659	+1.662	<.001	<.001	3	5
UCEC	DNAJC9 →	+0.413	+2.269	.002	<.001	3	5
UCEC	KIF11 →	+0.504	+1.265	.002	.002	3	5
UCEC	CENPH →	+0.506	+1.519	<.001	<.001	3	4
UCEC	BUB3 →	+0.353	+1.660	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,689 associations by consensus.

BIRC5 by BDP1 expression — UCEC

Explore this box plot interactively →