BDP1

Across TCGA patient cohorts, BDP1 mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BDP1-associated genes across cancer lineages are STAT3_pY705, FoxM1, and Cyclin-E2. Each is linked with BDP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both BDP1-to-partner and partner-to-BDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by BDP1-low versus BDP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BDP1→partner) and Y-score (partner→BDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.438	-2.044	<.001	<.001	3	4
BLCA	FoxM1 →	+0.253	+3.700	.001	.001	3	4
COAD	Cyclin-E2 →	+0.248	+3.025	.013	.018	3	4
COAD	ATM →	-0.621	-3.576	<.001	.002	3	3
COAD	TSC1 →	-0.360	-3.459	.002	.005	3	3
UCEC	TFRC →	+0.488	+2.415	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

STAT3_pY705 by BDP1 expression — UCEC

Explore this box plot interactively →