BDP1

Across TCGA cell cohorts, BDP1 mutation is significantly associated with the RNA expression of many other genes, with 1,635 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BDP1-associated genes across cancer lineages are GATAD2B, HEXIM2, and ZNF121. Each is linked with BDP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both BDP1-to-partner and partner-to-BDP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GATAD2B grouped by BDP1-low versus BDP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BDP1→partner) and Y-score (partner→BDP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GATAD2B →	+0.529	+3.237	.001	.003	3	3
LARGE_INTESTINE	HEXIM2 →	+0.587	+2.829	.001	<.001	3	3
LARGE_INTESTINE	ZNF121 →	+0.904	+2.743	<.001	.001	3	3
SOFT_TISSUE	RAB6D →	+0.064	+3.300	.002	.007	3	2
OVARY	HHLA1 →	+0.275	+3.949	<.001	.001	3	2
OVARY	CYP2C19 →	+0.373	+3.824	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,635 associations by consensus.

GATAD2B by BDP1 expression — LARGE_INTESTINE

Explore this box plot interactively →