BDKRB2

Across TCGA cell cohorts, BDKRB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,012 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BDKRB2-associated GO terms across cancer lineages are Plasma membrane organization, Positive regulation of protein localization to plasma membrane, and Negative regulation of intrinsic apoptotic signaling pathway. Each is linked with BDKRB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both BDKRB2-to-partner and partner-to-BDKRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane organization grouped by BDKRB2-low versus BDKRB2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BDKRB2→partner) and Y-score (partner→BDKRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Plasma membrane organization →	+0.153	+1.767	<.001	<.001	3	10
BONE	Positive regulation of protein localization to plasma membrane →	+0.114	+1.684	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of intrinsic apoptotic signaling pathway →	+0.075	+1.447	<.001	<.001	3	10
BONE	Vesicle-mediated transport to the plasma membrane →	+0.094	+2.515	<.001	<.001	3	10
LIVER	Protein stabilization →	+0.052	+1.581	<.001	.003	2	10
BONE	Protein targeting to ER →	+0.095	+1.867	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,012 associations by consensus.

Plasma membrane organization by BDKRB2 expression — BONE

Explore this box plot interactively →