BDKRB2

Across TCGA cell cohorts, BDKRB2 mutation is significantly associated with the RNA expression of many other genes, with 119 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BDKRB2-associated genes across cancer lineages are BMP15, MS4A14, and SPINK8. Each is linked with BDKRB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BDKRB2-to-partner and partner-to-BDKRB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMP15 grouped by BDKRB2-low versus BDKRB2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BDKRB2→partner) and Y-score (partner→BDKRB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	BMP15 →	+0.030	+4.906	<.001	.006	3	1
OESOPHAGUS	MS4A14 →	+0.053	+4.906	<.001	.006	3	1
OESOPHAGUS	SPINK8 →	+0.263	+4.906	<.001	.006	3	1
OESOPHAGUS	C2orf83 →	+0.020	+4.906	<.001	.006	3	1
LARGE_INTESTINE	CBY1 →	+0.628	+3.299	.002	.004	3	1
LARGE_INTESTINE	FZD3 →	+0.815	+3.212	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 119 associations by consensus.

BMP15 by BDKRB2 expression — OESOPHAGUS

Explore this box plot interactively →