BDH2

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, BDH2 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated BDH2 data layer compared with 24 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher BDH2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated BDH2 expression acts as an unfavorable survival marker.

LUSC are the cancer types where BDH2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUSCOSMedianAll0.1760.724.0189view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

BDH2–LUSC (OS)

Kaplan–Meier survival curve for BDH2 mutant vs wild-type samples in LUSC.

Open the LUSC breakdown →

Exploration