BDH2

Across TCGA cell cohorts, BDH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,122 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BDH2-associated GO terms across cancer lineages are Secondary metabolite biosynthetic process, Nonribosomal peptide biosynthetic process, and Box C/D sno(s)RNA metabolic process. Each is linked with BDH2 in more than 14 cancer types. Because this analysis shows association rather than direction, both BDH2-to-partner and partner-to-BDH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Secondary metabolite biosynthetic process grouped by BDH2-low versus BDH2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BDH2→partner) and Y-score (partner→BDH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Secondary metabolite biosynthetic process →	+1.638	+1.544	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Nonribosomal peptide biosynthetic process →	+0.159	+1.091	<.001	<.001	3	9
SOFT_TISSUE	Box C/D sno(s)RNA metabolic process →	+0.101	+1.654	.005	<.001	2	10
SOFT_TISSUE	Box C/D sno(s)RNA processing →	+0.101	+1.654	.005	<.001	2	10
SOFT_TISSUE	Box C/D sno(s)RNA 3'-end processing →	+0.101	+1.654	.005	<.001	2	10
PANCREAS	Response to staurosporine →	+0.126	+1.782	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,122 associations by consensus.

Secondary metabolite biosynthetic process by BDH2 expression — URINARY_TRACT

Explore this box plot interactively →