Across TCGA pan-cancer cohorts, BCRP4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of BCRP4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BCRP4 RNA is repressed in tumor relative to normal tissue. In most cancer types BCRP4 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH and COAD are the cancer types where BCRP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BCRP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.128	<.001	7	view →
COAD	All	II,III,IV	+0.049	.002	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: BCRP4 RNA expression & survival · all BCRP4 data types