BCORL1

Across TCGA pan-cancer cohorts, BCORL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated BCORL1 data layer compared with 25 for mass-spec protein and 13 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BCORL1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCORL1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

PDAC, LUAD, and UCEC are the cancer types where BCORL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	II,III,IV	0.426	0.812	.016	5	view →
LUAD	OS	Quartile	II,III,IV	0.906	0.614	.027	2	view →
UCEC	OS	Median	All	0.868	0.973	.041	2	view →
LSCC	DFS	Median	II,III,IV	0.341	1.000	.010	1	view →
GBM	OS	Quartile	All	0.737	0.921	.031	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

BCORL1–PDAC (DFS)

Open the PDAC breakdown →