Across TCGA pan-cancer cohorts, BCOR mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated BCOR data layer compared with 22 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher BCOR mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated BCOR expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where BCOR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	II,III,IV	0.539	0.290	.007	9	view →
CCRCC	DFS	Quartile	III,IV	0.920	0.244	.024	5	view →
GBM	OS	Tertile	All	0.374	0.730	.028	3	view →
LUAD	DFS	Tertile	All	1.000	0.907	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: BCOR tumor-vs-normal RNA expression · all BCOR data types