Across TCGA patient cohorts, BCO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,660 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BCO2-associated proteins across cancer lineages are BBS7, ADH5, and SETD7. Each is linked with BCO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both BCO2-to-partner and partner-to-BCO2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCO2→partner) and Y-score (partner→BCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BBS7 →	+0.309	+0.623	<.001	<.001	3	5
BRCA	ADH5 →	+0.352	+0.463	<.001	<.001	3	5
GBM	SETD7 →	+0.325	+0.451	<.001	.001	3	4
GBM	AURKB →	-0.785	-0.637	<.001	<.001	3	4
UCEC	BBS2 →	+0.426	+0.609	<.001	<.001	3	4
UCEC	CROCC →	+0.426	+0.521	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,660 associations by consensus.

Exploration

BCO2 survival (RNA) · tumor vs normal (RNA) · all BCO2 data types