Across TCGA patient cohorts, BCO2 protein abundance is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCO2-associated genes across cancer lineages are IQCD, CCDC113, and CHCHD3. Each is linked with BCO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCO2-to-partner and partner-to-BCO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCO2→partner) and Y-score (partner→BCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	IQCD →	-1.013	-1.066	.001	.003	3	2
GBM	CCDC113 →	+1.050	+0.682	.001	.003	3	1
GBM	CHCHD3 →	-0.375	-0.781	.008	.005	3	1
GBM	LHX2 →	-0.951	-0.488	.004	.008	3	1
GBM	NMRK1 →	+0.831	+0.677	.001	.002	3	1
GBM	CCSER2 →	-0.540	-0.708	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

Exploration

BCO2 survival (RNA) · tumor vs normal (RNA) · all BCO2 data types