Across TCGA patient cohorts, BCO2 mutation is significantly associated with the RNA expression of many other genes, with 5,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCO2-associated genes across cancer lineages are ATP5F1A, C18orf25, and OXA1L. Each is linked with BCO2 in more than 2 cancer types. Because this analysis shows association rather than direction, both BCO2-to-partner and partner-to-BCO2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCO2→partner) and Y-score (partner→BCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP5F1A →	+0.490	+2.258	.001	.001	3	3
UCEC	C18orf25 →	+0.526	+2.747	<.001	<.001	3	3
UCEC	OXA1L →	+0.267	+2.157	.007	.009	3	3
UCEC	PANK4 →	+0.453	+3.860	<.001	<.001	3	3
UCEC	NOLC1 →	+0.643	+3.103	<.001	<.001	3	3
UCEC	HDHD5 →	+0.659	+3.828	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,180 associations by consensus.

Exploration

BCO2 survival (RNA) · tumor vs normal (RNA) · all BCO2 data types