BCO1

Across TCGA pan-cancer cohorts, BCO1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated BCO1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher BCO1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCO1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

CCRCC and PDAC are the cancer types where BCO1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	III,IV	0.231	0.666	.009	8	view →
PDAC	OS	Median	All	0.702	0.407	.027	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

BCO1–CCRCC (DFS)

Open the CCRCC breakdown →