BCO1

Across TCGA patient cohorts, BCO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,583 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible BCO1-associated proteins across cancer lineages are PSMB10, MXRA5, and PEX1. Each is linked with BCO1 in more than 4 cancer types. Because this analysis shows association rather than direction, both BCO1-to-partner and partner-to-BCO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCO1 versus PSMB10 in BRCA, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCO1→partner) and Y-score (partner→BCO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PSMB10 →	+0.472	+0.365	.001	.001	3	5
GBM	MXRA5 →	-0.692	-0.716	<.001	<.001	3	4
LSCC	PEX1 →	+0.254	+0.577	.001	.001	3	4
LUAD	GSDMB →	+1.114	+1.001	<.001	<.001	3	4
BRCA	DDX60 →	+0.501	+0.334	<.001	.003	3	4
PDAC	KLC4 →	+0.359	+0.958	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,583 associations by consensus.

BCO1 vs PSMB10 — BRCA

Explore this scatter interactively →