BCL9P1

Across TCGA pan-cancer cohorts, BCL9P1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of BCL9P1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where BCL9P1 RNA is repressed in tumor relative to normal tissue. In most cancer types BCL9P1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and HNSC are the cancer types where BCL9P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BCL9P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	−0.159	<.001	8	view →
LUSC	Male	II,III,IV	−0.144	<.001	4	view →
HNSC	All	II,III,IV	+0.038	.009	4	view →
KIRC	All	All	+0.014	.005	4	view →
LIHC	All	All	+0.021	.007	3	view →
PRAD	All	All	−0.022	.005	2	view →
THCA	Male	III,IV	−0.021	.020	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

BCL9P1–LUAD

Open the LUAD breakdown →